Neurology Clinical Studies

Neurology Clinical Research in Columbus

Neurology clinical research is a critical step toward advancing medical research. Doctors use studies to progress current treatments, as well as develop new methods for neurological conditions.

Neurology is a branch of medicine dealing with disorders of the nervous system. Neurological disorders include Alzheimer’s disease, back pain, headaches and migraines, peripheral neuropathy, pinched nerves, and stroke. At Aventiv, we help further treatment for some of these conditions by offering clinical trials.

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Neurology Studies We Offer

At Aventiv, we offer a number of neurology studies. If you have any of the listed conditions, you may qualify for one of our clinical research studies. Please refer to each study’s page for detailed participant information.

Bacterial Vaginosis Study

Bacterial Vaginosis Trials at Aventiv Research Women’s Health

Aventiv Research is currently participating in an Bacterial Vaginosis study at our Women’s Health location in Columbus, Ohio. Bacterial vaginosis is a type of vaginal inflammation caused by the overgrowth of bacteria naturally found in the vagina, which upsets the natural balance. Clinical studies are an important step to understanding the cause of and finding treatment for Bacterial Vaginosis.

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Bacterial Vaginosis Study

The primary objective of the study is to assess the efficacy of an investigational drug for the treatment of Bacterial Vaginosis in postmenarchal females. You may qualify for this study if you:

  • are female and at least 12 years of age
  • have a clinical diagnosis of of bacterial vaginosis

Participants from 12 through 17 years old may participate where permitted and with appropriate consent from the parent(s)/guardian(s) and assent from the patient.

 

Endometriosis Study

Endometriosis Trials at Aventiv Research Women’s Health

Aventiv Research is currently participating in an Endometriosis study at our Women’s Health location in Columbus, Ohio. Endometriosis is an often painful disorder in which tissue similar to the tissue that normally lines the inside of your uterus — the endometrium — grows outside your uterus. Endometriosis most commonly involves your ovaries, fallopian tubes and the tissue lining your pelvis. Endometriosis can cause pain especially during menstrual periods. Clinical studies are an important step to understanding the cause of and finding treatment for Endometriosis.

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Endometriosis Study

The primary objective of this study is to assess the efficacy of an investigational drug on nonmenstrual pelvic pain in women with endometriosis. You may qualify for this study if:

  • you are a female, 18 to 49 years old
  • have a documented surgical/laparoscopy diagnosis of endometriosis

 

Chikungunya Vaccine Study

Chikungunya Vaccine Trials in Columbus

Aventiv Research is currently participating in a chikungunya vaccine study at our Columbus, Ohio location. Chikungunya is a viral disease transmitted to humans by infected mosquitoes. The symptoms of chikungunya are similar to those of dengue and Zika—diseases spread by the same mosquitoes that transmit chikungunya. It causes fever and severe joint pain. Other symptoms include muscle pain, headache, nausea, fatigue and rash. Like any other drug, a new vaccine must be tested on human subjects before being approved for use by the Federal Drug Administration (FDA).

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Chikungunya Vaccine Study

The primary objective of this clinical trial is to evaluate the safety of an investigational novel vaccine in healthy adults and adolescents. You may qualify for this study if you’re 12-64 years of age and are:

  • A healthy volunteer who is overtly healthy as determined by medical evaluation

As a part of our ongoing commitment to protect your health and safety, we’re practicing enhanced safety measures at our clinical research sites.

Vaccine Immunology Clinical Studies

Vaccine Clinical Research in Columbus

Clinical research serves a vital role in the development of novel (new) vaccine candidates. Because vaccines are given to millions of healthy people to prevent serious diseases, they’re held to very high safety standards. A new vaccine must be evaluated for safety, immunogenicity, and protective efficacy in humans before it is licensed for use by the Food and Drug Administration (FDA) and recommended for use by the Centers for Disease Control and Prevention (CDC).

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Vaccine Trials We Offer

At Aventiv, we offer a number of vaccine candidate trials. During a clinical trial, an investigational vaccine is tested on healthy people who volunteer to get vaccinated. A healthy volunteer is someone with no known significant health problems who participates in research to test a new drug, device, or intervention. Your participation in a clinical trial could lead to a new treatment that helps someone you care about. Please refer to each study’s page for detailed participant information.

Low Testosterone Study

Low Testosterone Trials in Columbus

Aventiv Research is currently participating in a low testosterone study at our Columbus, Ohio location. Hypogonadism (Low-T) is characterized by a decline in testosterone and subsequently, a decline in sex drive. Low-T can be caused by many factors, including age, other health problems like diabetes, obesity, or high blood pressure, and genetic conditions. Clinical trials are a necessary part of finding treatment for Low-T.

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Low Testosterone Study

The primary objective of this study is to compare the effect of testosterone replacement therapy and placebo in symptomatic hypogonadal men with increased risk for cardiovascular disease. You may be eligible to participate if:

  • You are male, and between 45 and 80 years of age
  • Have been diagnosed with or have the presence of at least one symptom of low testosterone such as:
    • decreased sex drive
    • decrease in spontaneous/morning erections
    • a significant decrease in energy

And

  • Have pre-existing cardiovascular disease

Acute Migraine Study

Migraine Trials in Columbus

Aventiv Research is currently participating in the RELIEF acute migraine study at our Columbus, Ohio location.  Researchers believe that migraines may be caused by a central nervous system disorder, irregularities with blood vessels in the brain, chemical abnormalities, or genetics. Clinical studies are an important step to understanding the cause and finding a solution to prevent migraines.

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RELIEF Acute Migraine Clinical Trial

The objective of this study is to evaluate the efficacy and safety of an investigational drug for active migraine in adults. You maybe be eligible to participate in this study if you:

  • Are 18 to 75 years of age
  • Have experienced migraines for 1 year or more, starting before age 50
  • Have had migraines on 4-15 days per month in each of the last 3 months
  • Have migraines that, if left untreated:
    • Cause headache pain of moderate to severe intensity as well as symptoms such as nausea, light sensitivity, or sound sensitivity
    • Last between 4 and 72 hours

Facial Wrinkles Study

Facial Wrinkles Trials in Columbus

Aventiv Research is currently participating in a moderate to severe facial wrinkles study at our Dublin, Ohio location. Glabella lines (frown lines) are the short vertical lines found between the eyebrows and extending up the central forehead. They are often the first wrinkles to appear on the forehead even as early as the mid 20’s. Glabella lines make a person feel tired and angry. The effect of constantly contracting the glabella muscles contributes to headaches and central forehead heaviness. Glabella lines are particularly deep looking because the skin in the glabella is thick compared to the eyelid skin at the outer end of the eyes which is very thin and develops Lateral Canthal Lines, the finer wrinkles called crow’s feet.

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Facial Wrinkles Study

The primary objective of this clinical trial is to is to assess the efficacy and safety of an investigational drug for long-term treatment of moderate to severe Glabellar Lines (frown lines) and Lateral Canthal Lines (crow’s feet). You may be eligible to participate if:

  • You are at least 18 years of age
  • You have moderate to severe face wrinkles

And

  • You have NOT used any Botulinum toxin in facial areas in the past 9 months

Moderate to Severe Asthma Study

Asthma Trials in Columbus

Aventiv Research is currently participating in a moderate to severe asthma Study at our Dublin, Ohio location. Asthma is a chronic lung disease that affects about 1 in 12 people, and that number continues to grow. The disease inflames and narrows airways, thus causing periods of chest tightness, coughing, shortness of breath, and wheezing on a recurring basis.

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Moderate to Severe Asthma Study

The primary objective of this clinical trial is to evaluate the efficacy of budesonide/albuterol metered-dose inhaler compared to albuterol metered-dose inhaler administered as needed in response to symptoms. If you have been diagnosed with asthma and have frequent severe attacks and active symptoms despite using preventative medications, you may be interested in a new investigational medication for the treatment of adults with moderate to severe asthma.

You may qualify for the MANDALA study if:

  • At least 4 years of age or older
  • Diagnosed with asthma
  • Taking medications for asthma
  • Having asthma exacerbations (worsening of asthma and/or increasing severity of breathing problems)

COVID-19 Vaccine Study

COVID-19 Vaccine Trials in Columbus

Aventiv Research is currently participating in an investigational COVID-19 vaccine study at our Columbus, Ohio location. You can join the fight against COVID-19 by volunteering. Like any other drug, a new vaccine must be tested on human subjects before being approved for use by the Federal Drug Administration (FDA).

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COVID-19 Vaccine Study

The primary objective of this clinical trial is to evaluate the safety, tolerability, immunogenicity, and potential efficacy of a SARS-CoV-2 RNA vaccine candidate against COVID-19.

We are specifically looking for volunteers who are:

  • Adolescents 12 to 17 years of age who are overtly healthy as determined by medical evaluation

As a part of our ongoing commitment to protect your health and safety, we’re practicing enhanced safety measures at our clinical research sites.