Metabolic Acidosis Study

Metabolic Acidosis Trials in Phoenix

Aventiv Research is currently participating in a metabolic acidosis study at our Phoenix, AZ location. Metabolic acidosis is a buildup of acid in your body. Your kidneys help keep the right balance of acids in your body. Your body can have too much acid for two main reasons: 1) your kidneys are not balancing or getting rid of enough acid or 2) your body is making too much acid. Metabolic acidosis is common in people with kidney disease because their kidneys are not filtering their blood well enough. Advances in drug therapy are key to treating this disease in its early stages and preventing further damage.

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Metabolic Acidosis Clinical Trial

The objective of this study is to evaluate the effect of an investigational drug on the progression of chronic kidney disease and to evaluate its safety profile in chronic kidney disease patients with metabolic acidosis. You maybe be eligible to participate in this study if you:

  • Are between 18 and 85 years of age
  • Have been diagnosed with chronic kidney disease
  • Have low serum bicarbonate meeting the study criteria
  • Have stable renal function

FSGS, TR-MCD, and DN Study

FSGS, TR-MCD, and DN Trials in Phoenix

Aventiv Research is currently participating in an FSGS, TR-MCD, and DN study at our Phoenix, AZ location. Currently, there are no approved therapies in the US to specifically treat Focal Segmental Glomerulosclerosis (FSGS) or Treatment Resistant Minimal Change Disease (TR-MCD). Despite current treatments for Diabetic Nephropathy (DN), patients continue to experience progressive loss of kidney function. Given this there is a need to develop new therapies to treat patients with FSGS, TR-MCD, and DN. Advances in drug therapy are key to treating these diseases in their early stages and preventing further damage.

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FSGS, TR-MCD, and DN Clinical Trial

The objective of this study is to evaluate the safety and efficacy of an investigational medication for the treatment of Diabetic Nephropathy (DN), Focal Segmental Glomerulosclerosis (FSGS), and Treatment Resistant Minimal Change Disease (TR-MCD). You may be be eligible to participate in this study if you:

  • Are between 18 and 75 years of age
  • Have been diagnosed with Diabetic Nephropathy (DN)

OR

  • Focal Segmental Glomerulosclerosis (FSGS) AND Treatment Resistant Minimal Change Disease (TR-MCD)

Diabetic Kidney Disease Study

Diabetic Kidney Disease Trials in Phoenix

Aventiv Research is currently participating in a diabetic kidney disease study at our Phoenix, AZ location. Diabetic kidney disease (DKD), also known as diabetic nephropathy, is a serious kidney-related complication of type 1 diabetes and type 2 diabetes. About 25% of people with diabetes eventually develop kidney disease. Advances in drug therapy are key to treating this disease at its early stages and preventing further damage.

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Diabetic Kidney Disease Clinical Trial

The objective of this study is to evaluate the efficacy and safety of an investigational medication in patients with diabetic kidney disease. You maybe be eligible to participate in this study if you:

  • Are at least 18 years of age
  • Have chronic kidney disease AND type 2 diabetes
  • Have stable blood pressure

Cardio-Renal Outcomes in Chronic Kidney Disease Study

Cardio-Renal Outcomes in Chronic Kidney Disease Trials in Phoenix

Aventiv Research is currently participating in an chronic kidney disease study to asses cardio-renal outcomes at our Phoenix, AZ location. Chronic kidney disease (CKD) describes the gradual loss of kidney function. Chronic kidney disease may not become apparent until your kidney function is significantly impaired. Treatment for chronic kidney disease focuses on slowing the progression of the kidney damage, usually by controlling the underlying cause. Advances in drug therapy are key to treating this disease at its early stages and preventing further damage.

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Cardio-Renal Outcomes in Chronic Kidney Disease Clinical Trial

The objective of this study is to assess cardio-renal outcomes from an investigational drug versus placebo in patients with chronic kidney disease. You maybe be eligible to participate in this study if you are:

  • At least 18 years of age
  • Have progressive chronic kidney disease

and do NOT:

  • Currently need an SGLT-2 or SGLT-1/2 inhibitor

Chronic Kidney Disease with IgA Nephropathy or Diabetes Study

Chronic Kidney Disease with IgA Nephropathy or Diabetes Trials in Phoenix

Aventiv Research is currently participating in a study for people who have chronic kidney disease with IgA nephropathy or diabetes at at our Phoenix, AZ location. Chronic kidney disease (CKD) describes the gradual loss of kidney function. Treatment for CKD focuses on slowing the progression of the kidney damage, usually by controlling the underlying cause. Diabetes is the leading cause of kidney failure, accounting for 44% percent of new cases. Current research suggests that control of high blood pressure is a key factor in slowing this disease. IgA nephropathy (also known as Berger’s disease) is one of the most common kidney diseases. It causes damage to the tiny filters inside the kidneys. This damage can cause CKD and can lead to kidney failure. Advances in drug therapies for these indications are key to treating this disease at its early stages and preventing further damage.

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Chronic Kidney Disease with IgA Nephropathy or Diabetes Clinical Trial

The objective of this study is to evaluate the safety, efficacy, tolerability, PD, and PK profile of an investigational drug in patients with chronic kidney disease with IgA nephropathy or diabetes. You maybe be eligible to participate in this study if you are at least 18 years of age, have chronic kidney disease and meet ONE of the three following criteria:

  • be African American with hypertension

OR

  • have IgA nephropathy

OR

  • have type 2 diabetes with hypertension

COVID-19 Antibody Treatment Study

COVID-19 Antibody Treatment Trials in Columbus

Aventiv Research is currently participating in an investigational COVID-19 monoclonal antibody (mAb) treatment study at our Columbus, Ohio location. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in the pandemic spread of coronavirus disease 2019 (COVID-19), which in critical cases results in pulmonary failure, respiratory complications, and death. There is an urgent need for effective therapeutics to modify disease outcomes. You can join the fight against COVID-19 by volunteering.

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COVID-19 Monoclonal Antibody (mAb) Treatment Study

The primary objective of this clinical trial is to characterize the effect of an investigational drug, compared to placebo, on SARS-CoV-2 viral load and viral clearance.  You may qualify for this study if you are an adult who is currently not hospitalized and have one or more mild or moderate COVID-19 symptoms such as fever, cough, sore throat, malaise, headache, muscle pain, gastrointestinal symptoms, or shortness of breath with exertion.

We are specifically looking for adults who have at least one of the following high-risk factors:

  • Are at least 65 years of age
  • Have a BMI greater than 35
  • Have chronic kidney disease
  • Have diabetes
  • Have immunosuppressive disease
  • Are currently receiving immunosuppressive treatment
  • Are at least 55 years of age AND have
    • cardiovascular disease, OR
    • hypertension, OR
    • chronic obstructive pulmonary disease

As a part of our ongoing commitment to protect your health and safety, we’re practicing enhanced safety measures at our clinical research sites.

Diabetic Peripheral Neuropathic Pain Study

Diabetic Peripheral Neuropathic Pain Trials in Columbus

Aventiv Research is currently participating in an diabetic peripheral neuropathic pain study at our Columbus, Ohio location. Diabetic neuropathy is a type of nerve damage that can occur if you have diabetes. Depending on the affected nerves, diabetic neuropathy symptoms can range from pain and numbness in your legs and feet to problems with your digestive system, urinary tract, blood vessels and heart. Some people have mild symptoms. But for others, diabetic neuropathy can be quite painful and disabling.

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Diabetic Peripheral Neuropathic Pain Clinical Trial

The objective of this study is to evaluate the efficacy and safety of an investigational drug for the treatment of diabetic peripheral neuropathic pain in adults. You maybe be eligible to participate in this study if you:

  • Are at least 18 years of age
  • Have diabetic neuropathy
  • Are willing to discontinue all pain medications you are using for diabetic peripheral neuropathic pain, except rescue medication, until the follow-up period

Neurology Clinical Studies

Neurology Clinical Research in Columbus

Neurology clinical research is a critical step toward advancing medical research. Doctors use studies to progress current treatments, as well as develop new methods for neurological conditions.

Neurology is a branch of medicine dealing with disorders of the nervous system. Neurological disorders include Alzheimer’s disease, back pain, headaches and migraines, peripheral neuropathy, pinched nerves, and stroke. At Aventiv, we help further treatment for some of these conditions by offering clinical trials.

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Neurology Studies We Offer

At Aventiv, we offer a number of neurology studies. If you have any of the listed conditions, you may qualify for one of our clinical research studies. Please refer to each study’s page for detailed participant information.

Bacterial Vaginosis Study

Bacterial Vaginosis Trials at Aventiv Research Women’s Health

Aventiv Research is currently participating in an Bacterial Vaginosis study at our Women’s Health location in Columbus, Ohio. Bacterial vaginosis is a type of vaginal inflammation caused by the overgrowth of bacteria naturally found in the vagina, which upsets the natural balance. Clinical studies are an important step to understanding the cause of and finding treatment for Bacterial Vaginosis.

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Bacterial Vaginosis Study

The primary objective of the study is to assess the efficacy of an investigational drug for the treatment of Bacterial Vaginosis in postmenarchal females. You may qualify for this study if you:

  • are female and at least 12 years of age
  • have a clinical diagnosis of of bacterial vaginosis

Participants from 12 through 17 years old may participate where permitted and with appropriate consent from the parent(s)/guardian(s) and assent from the patient.

 

Endometriosis Study

Endometriosis Trials at Aventiv Research Women’s Health

Aventiv Research is currently participating in an Endometriosis study at our Women’s Health location in Columbus, Ohio. Endometriosis is an often painful disorder in which tissue similar to the tissue that normally lines the inside of your uterus — the endometrium — grows outside your uterus. Endometriosis most commonly involves your ovaries, fallopian tubes and the tissue lining your pelvis. Endometriosis can cause pain especially during menstrual periods. Clinical studies are an important step to understanding the cause of and finding treatment for Endometriosis.

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Endometriosis Study

The primary objective of this study is to assess the efficacy of an investigational drug on nonmenstrual pelvic pain in women with endometriosis. You may qualify for this study if:

  • you are a female, 18 to 49 years old
  • have a documented surgical/laparoscopy diagnosis of endometriosis